« Back
Home /
Fidaxomicin (OPT-80)

Fidaxomicin (OPT-80)

Item no.	V1465-100mg
Manufacturer	InvivoChem LLC
CASRN	873857-62-6
Amount	100 mg
Quantity options	1 g 250 mg 500 mg 50 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1465CAS #:873857-62-6Purity >=98% Description: Fidaxomicin (formerlyOPT-80, PAR-101; PAR101; OPT80; Dificid; Dificlir; Clostomicin B1; Difimicin; Lipiarmycin; Tiacumicin B) is a narrow spectrum macrocyclic antibiotic agent and a naturally occuring fermentation product extracted from the actinomycete Dactylosporangium aurantiacum subspecies hamdenesisthat. Fidaxomicin acts as an RNA polymerase inhibitor by binding to the DNA template–RNA polymerase (RNAP) complex prior to the formation of the open RNAP-DNA complex in which transcription is initiated. Description: References: Clin Infect Dis. 2012 Feb 15; 54(4):568-74. References:
Molecular Weight (MW)	1058.04
Formula	C52H74Cl2O18
CAS No.	873857-62-6
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (94.5 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: (2R, 3S, 4S, 5S, 6R)-6-({(3E, 5E, 8S, 9E, 11S, 12R, 13E, 15E, 18S)-12-{[(2R, 3S, 4R, 5S)-3, 4-Dihydroxy-5-(isobutyryloxy)-6, 6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9, 13, 15- trimethyl-2-oxooxacyclooctadeca-3, 5, 9, 13, 15-pentaen-3-yl}methoxy)-4-hydroxy-5-methoxy-2-methyltetrahydro-2H-pyran-3-yl 3, 5-dichloro-2-ethyl-4, 6-dihydroxybenzoate InChi Key: ZVGNESXIJDCBKN-UUEYKCAUSA-N InChi Code: InChI=1S/C52H74Cl2O18/c1-13-30-22-26(6)33(56)18-16-15-17-31(23-66-51-45(65-12)42(61)44(29(9)67-51)69-49(64)35-32(14-2)36(53)39(58)37(54)38(35)57)48(63)68-34(28(8)55)20-19-25(5)21-27(7)43(30)70-50-41(60)40(59)46(52(10, 11)72-50)71-47(62)24(3)4/h15-17, 19, 21-22, 24, 28-30, 33-34, 40-46, 50-51, 55-61H, 13-14, 18, 20, 23H2, 1-12H3/b16-15+, 25-19+, 26-22+, 27-21+, 31-17+/t28-, 29-, 30+, 33+, 34+, 40-, 41+, 42+, 43+, 44-, 45+, 46+, 50-, 51-/m1/s1 SMILES Code: O=C(O[CH]1[CH](C)O[CH](OC/C2=C\C=C\C[CH](O)/C(C)=C/[CH](CC)[CH](O[CH]3[CH](O)[CH](O)[CH](OC(C(C)C)=O)C(C)(C)O3)/C(C)=C/C(C)=C/C[CH]([CH](O)C)OC2=O)[CH](OC)[CH]1O)C4=C(O)C(Cl)=C(O)C(Cl)=C4CC
Synonyms	PAR101; OPT80; PAR 101; OPT-80; PAR-101; OPT 80; Dificid; Dificlir; Clostomicin B1; Difimicin; Lipiarmycin; Tiacumicin B.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 mg

available

Delivery expected until 10/2/2025

Express Delivery: Save 15 days

Compare

Add to wishlist

Get an offer