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Description: Nedaplatin (formerly NSC-375101D; NSC 37510D; NSC-375101 D; NSC 375101-D; trade name Aqupla) is a cisplatin analog and DNA damaging agent approved as an anticancer medication. It inhibits tumor colony formation with an IC50 of 94 uM. Nedaplatin is a platinum compound used for cancer chemotherapy but produces less side effects such as nausea, vomiting and nephrotoxicity than other platinum-containing drugs.
References: Cancer Chemother Pharmacol. 1997; 39(6):493-7; Eur J Cancer. 1998 Oct; 34(11):1796-801.
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