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Ki16425 (Debio 0719)

Ki16425 (Debio 0719)

Item no.	V1496-50mg
Manufacturer	InvivoChem LLC
CASRN	355025-24-0
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1496CAS #:355025-24-0Purity >=98% Description: Ki16425 (also called Ki 16425; Debio-0719; Ki-16425; Debio 0719) is a competitive, selective and reversible antagonist of LPA which inhibits LPA1, LPA2 and LPA3 with Ki values of 0.34 uM, 6.5 uM and 0.93 uM in RH7777 cell lines, respectively. Ki16425 reduces nerve growth factor-induced neurite outgrowth in pheochromocytoma 12 cells. ki16425 blunts abdominal and systemic inflammation in a mouse model of peritoneal sepsis. Description: References: Mol Pharmacol. 2003 Oct; 64(4):994-1005; J Neurochem. 2006 Sep; 98(6):1920-9; J Neurochem. 2009 Apr; 109(2):603-10. References:
Molecular Weight (MW)	474.96
Formula	C23H23ClN2O5S
CAS No.	355025-24-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 94 mg/mL (197.9 mM)
	Water: < 1 mg/mL
	Ethanol: 94 mg/mL (197.9 mM)
Solubility (In vivo)	5% DMSO+95% Corn oil: 30 mg/mL
Synonyms	Ki16425; Debio0719; Ki-16425; Debio 0719; Ki 16425; Debio-0719

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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Delivery expected until 11/6/2025

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