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APY0201

APY0201

Item no.	V1558-10mg
Manufacturer	InvivoChem LLC
CASRN	1232221-74-7
Amount	10 mg
Quantity options	100 mg 1 mg 250 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1558CAS #: 1232221-74-7Purity >=98% Description: APY0201 is a novel, potent and selective PIKfyve inhibitor, which inhibits the conversion of PtdIns3P to PtdIns(3, 5)P2 in the presence of in the presence of 33PATP with an IC50 of 5.2 nM. APY0201 also inhibits IL-12/23 production. It is a unique small molecular IL-12/23 production inhibitor, from activated macrophages and monocytes, and demonstrate ameliorated inflammation in an experimental model of colitis. Description: References:Bioorg Med Chem. 2014 Jun 1; 22(11):3021-9. References:
Molecular Weight (MW)	413.48
Formula	C23H23N7O
CAS No.	1232221-74-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: >= 35 mg/mL
	Water: < 1 mg/mL
	Ethanol: N/A
Other info	Chemical Name: (E)-4-(5-(2-(3-methylbenzylidene)hydrazinyl)-2-(pyridin-4-yl)pyrazolo[1, 5-a]pyrimidin-7-yl)morpholine InChi Key: RFZQYGBLRIKROZ-PCLIKHOPSA-N InChi Code: InChI=1S/C23H23N7O/c1-17-3-2-4-18(13-17)16-25-27-21-15-23(29-9-11-31-12-10-29)30-22(26-21)14-20(28-30)19-5-7-24-8-6-19/h2-8, 13-16H, 9-12H2, 1H3, (H, 26, 27)/b25-16+ SMILES Code: CC1=CC(/C=N/NC2=NC3=CC(C4=CC=NC=C4)=NN3C(N5CCOCC5)=C2)=CC=C1
Synonyms	APY0201; APY-0201; APY 0201.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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Delivery expected until 9/4/2025

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