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A-205804

A-205804

Item no.	V1598-100mg
Manufacturer	InvivoChem LLC
CASRN	251992-66-2
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1598CAS #:251992-66-2Purity >=98% Description: A-205804 is a novel, potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively. When tested with primary HUVECs cells, A-205804 treatment reduced cell migration ability by inhibiting the expression of E-selectin and ICAM-1. In human vascular endothelial cells using whole-cell high-throughput assay, it was shown that A-205804 exhibited potent and selective inhibition to E-selectin and ICAM-1 with low concentrations. References: J Med Chem. 2001 Oct 11; 44(21):3469-87; J Med Chem. 2001 Mar 15; 44(6):988-1002.
Molecular Weight (MW)	300.4
Formula	C15H12N2OS2
CAS No.	251992-66-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 60 mg/mL (199.7 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 4-[(4-Methylphenyl)thio]thieno[2, 3-c]pyridine-2-carboxamide InChi Key: QQGWEXFLMJGCAL-UHFFFAOYSA-N InChi Code: 1S/C15H12N2OS2/c1-9-2-4-10(5-3-9)19-13-7-17-8-14-11(13)6-12(20-14)15(16)18/h2-8H, 1H3, (H2, 16, 18) SMILES Code: CC1=CC=C(SC2=C3C=C(SC3=CN=C2)C(N)=O)C=C1
Synonyms	A205804; A-205804; A 205804

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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