INH6

Item no.	V1613-500mg
Manufacturer	InvivoChem LLC
CASRN	1001753-24-7
Amount	500 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1613CAS #:1001753-24-7Purity >=98% Description: INH6 is a potent and cell-permeable Hec1 inhibitor, which specifically disrupts the Hec1/Nek2 interaction and causes chromosome mis-alignment. INH6 inhibited Hec1/Nek2 function through protein degradation that led to chromosome mis-segregation and cell death. In MDA-MB468 and MDA-MB231 human breast cancer cell lines, HeLa human cervical cancer line and K562 human erythromyeloblastoid leukemia cell line, INH6 exhibited significantly anti-proliferation activities with IC50 values of 2.1, 1.7, 2.4 and 2.5 uM, respectively. References: J Med Chem. 2009 Mar 26; 52(6):1757-67.
Molecular Weight (MW)	322.42
Formula	C19H18N2OS
CAS No.	1001753-24-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 64 mg/mL (198.5 mM)
	Water: < 1 mg/mL
	Ethanol: 11 mg/mL (34.1 mM)
Other info	Chemical Name: N-[4-(2, 4, 6-Trimethylphenyl)-1, 3-thiazol-2-yl]benzamide InChi Key: WCZLNJTXHZPHLM-UHFFFAOYSA-N InChi Code: InChI=1S/C19H18N2OS/c1-12-9-13(2)17(14(3)10-12)16-11-23-19(20-16)21-18(22)15-7-5-4-6-8-15/h4-11H, 1-3H3, (H, 20, 21, 22) SMILES Code: O=C(NC1=NC(C2=C(C)C=C(C)C=C2C)=CS1)C3=CC=CC=C3
Synonyms	INH6; INH-6; INH 6

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Amount: 500 mg

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