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Vinblastine (Vincaleukoblastine)

Vinblastine (Vincaleukoblastine)

Item no.	V1621-500mg
Manufacturer	InvivoChem LLC
CASRN	865-21-4
Amount	500 mg
Quantity options	100 mg 10 mg 1 g 250 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1621CAS #:865-21-4Purity >=98% Description: Vinblastine (also known as NSC49842; Vincaleukoblastine), a naturally occuriong alkaloid isolated from the plant Vinca rosea Linn, is an approved anticancer drug acting as a potent mitotic inhibitor that inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 uM in a cell-free assay, it is used to treat certain kinds of cancer. Vinblastine binds to tubulin and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the M phase of the cell cycle. References: Proc Soc Exp Biol Med. 1993 Jul; 203(3):372-6; Oncogene. 2003 Sep 25; 22(41):6458-61. Related CAS #:143-67-9 (sulfate) 865-21-4 (free)
Molecular Weight (MW)	810.97
Formula	C46H58N4O9
CAS No.	865-21-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (110.0 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Chemical Name	(3aR, 3a1R, 4R, 5S, 5aR, 10bR)-methyl 4-acetoxy-3a-ethyl-9-((5S, 7R, 9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-2, 4, 5, 6, 7, 8, 9, 10-octahydro-1H-3, 7-methano[1]azacycloundecino[5, 4-b]indol-9-yl)-5-hydroxy-8-methoxy-6-methyl-3a, 3a1, 4, 5, 5a, 6, 11, 12-octahydro-1H-indolizino[8, 1-cd]carbazole-5-carboxylate
Synonyms	NSC49842; NSC-49842; NSC 49842; Vincaleucoblastine, Velban, Velsar, VLB

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Amount: 500 mg

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Delivery expected until 10/2/2025

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