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vinflunine-tartrate

vinflunine-tartrate

Item no.	V1625-50mg
Manufacturer	InvivoChem LLC
CASRN	1201898-17-0
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1625CAS #:1201898-17-0 Purity >=98% Description: Vinflunine Tartrate (F 12158, BMS; 710485) is a new analog of the vinca alkaloid vinorelbine that is bi-fluorinated strucuturally. As a mitotic or tubulin inhibitor, it has anticancer, anti-angiogenic, vascular-disrupting and anti-metastatic properties. The major effects of Vinflunine on dynamic instability are a slowing of the microtubule growth rate, an increase in growth duration, and a reduction in shortening duration. The effects of Vinflunine on the readmilling rate is examined by following 3HGTP incorporation into MAP-rich microtubules, and the IC50 is 0.42 uM. F 12158, BMS; 710485 References: Cancer Res. 2000; 60(18):5045-51; Biochemistry. 2000; 39(39):12053-62; Eur J Cancer. 2006; 42(16):2821-32. Related CAS#: 194468-36-5 (ditartrate); 162652-95-1 (free base); 1201898-17-0 (tartrate) 1201898-17-0 (tartrate)
Molecular Weight (MW)	967.02
Formula	C45H54F2N4O8.xC4H6O6
CAS No.	1201898-17-0 (tartrate);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (103.4 mM)
	Water: 66 mg/mL (68.3 mM)
	Ethanol: 11 mg/mL (11.4 mM)
Solubility (In vivo)	Saline: 30 mg/mL
Synonyms	Vinflunine; Vinflunine tartrate; vinflunine ditartrate; F 12158, F-12158, F12158, BMS 710485, BMS710485, BMS-710485

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Amount: 50 mg

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