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Description: Doxorubicin-MVCP, formerly known as MC-Val-Cit-PAB-Doxorubicin, is a Doxorubicin analogue with a MC-Val-Cit-PAB linker. Mc-Val-Cit-PAB is a cathepsin cleavable ADC peptide linker. Doxorubicin-MVCP can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers. Doxorubicin-MVCP is a useful agent to make Doxorubicin-conjugate for drug delivery, nanodrug research.
References: Optimization of a Stable Linker Involved DEVD Peptide-Doxorubicin Conjugate That Is Activated upon Radiation-Induced Caspase-3-Mediated Apoptosis. J Med Chem. 2015 Aug 27; 58(16):6435-47. doi: 10.1021/acs.jmedchem.5b00420. Epub 2015 Aug 18. PubMed PMID: 26263187.
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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