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Procaine HCl (Novocaine)

Procaine HCl (Novocaine)

Item no.	V1666-2g
Manufacturer	InvivoChem LLC
CASRN	51-05-8
Amount	2 g
Quantity options	100 g 10 g 1 g 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1666CAS #:51-05-8Purity >=98% Description: Procaine HCl (also known as Novocaine HCl), the HCl salt of the local anesthetic Procaine, is an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 uM, 0.296 mM and 45.5 uM, which is also an inhibitor of 5-HT3 with KD of 1.7 uM. Procaine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. Procaine has also been shown to bind or antagonize the function of N-methyl-D-aspartate (NMDA) receptors as well as nicotinic acetylcholine receptors and the serotonin receptor-ion channel complex. References: Anesth Analg. 1998 Oct; 87(4):885-9; Br J Anaesth. 2006 Jan; 96(1):77-87. Related CAS #:51-06-9 (free base) 51-05-8 (HCl)
Molecular Weight (MW)	272.77
Formula	C13H20N2O2.HCl
CAS No.	51-05-8
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 55 mg/mL (201.6 mM)
	Water: 55 mg/mL (201.6 mM)
	Ethanol: < 1 mg/mL
Solubility (In vivo)	Chemical Name: 2-(diethylamino)ethyl 4-aminobenzoate; hydrochloride InChi Key: HCBIBCJNVBAKAB-UHFFFAOYSA-N InChi Code: InChI=1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11; /h5-8H, 3-4, 9-10, 14H2, 1-2H3; 1H SMILES Code: CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.Cl
Synonyms	Novocaine HCl; Procaine Hydrochloride; Procaine HCl; Novocaine hydrochloride; Gerovital H3; Aminocaine

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Amount: 2 g

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