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Glyburide (Glibenclamide)

Glyburide (Glibenclamide)

Item no.	V1678-5g
Manufacturer	InvivoChem LLC
CASRN	10238-21-8
Amount	5 g
Quantity options	100 g 10 g 1 g 2 g 50 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1678CAS #:10238-21-8Purity >=98% Description: Glyburide (also known as Glibenclamide) is a known and selective blocker of vascular ATP-sensitive K+ channels (KATP). Glyburide is an antidiabetic sulfonylurea derivative used in the treatment of type 2 diabetes. Its actions are similar to those of chlorpropamide that can potentially be used to decrease cerebral edema. References: J Pharmacol Exp Ther. 1989 Jan; 248(1):149-56; J Pharmacol Exp Ther. 1993 May; 265(2):933-7.
Molecular Weight (MW)	494
Formula	C23H28ClN3O5S
CAS No.	10238-21-8
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 99 mg/mL (200.4 mM)
	Water:< 1 mg/mL
	Ethanol:< 1 mg/mL
Other info	Chemical Name: 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide InChi Key: ZNNLBTZKUZBEKO-UHFFFAOYSA-N InChi Code: InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30, 31)27-23(29)26-18-5-3-2-4-6-18/h7-12, 15, 18H, 2-6, 13-14H2, 1H3, (H, 25, 28)(H2, 26, 27, 29) SMILES Code: COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
Synonyms	HB-420; HB419; HB420; Glyburide; Glibenclamide; Glybenclamide; Micronase; Diabeta; Maninil; Micronase; Neogluconin

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Amount: 5 g

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Delivery expected until 10/2/2025

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