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Description: Esomeprazole Sodium (known as Nexium, H-199 and S-Omeprazole sodium) is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg. Esomeprazole Sodium is the S-isomer of omeprazole and acts as a proton pump inhibitor gastric antisecretory agent indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis.
References: Eur J Clin Pharmacol. 2008 Oct; 64(10):935-51.
Related CAS#: 95510-70-6(sodium); 119141-88-7 (S-isomer); 95510-71-7 (potassium); 73590-85-9(Omeprazole metabolite Omeprazole sulfide; Ufiprazole; Omeprazolesulfide); 88546-55-8 (Omeprazole metabolite Omeprazole sulfone; Omeprazole sulfone; Omeprazole sulphone); 922731-01-9 (Omeprazole D3; H16868 D3); 73590-58-6 (free form); 161973-10-0 (Esomeprazole magnesium); 217087-09-7 (Esomeprazole Magnesium trihydrate)
Chemical Name: sodium (S)-5-methoxy-2-(((4-methoxy-3, 5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
InChi Key: RYXPMWYHEBGTRV-JIDHJSLPSA-N
InChi Code: InChI=1S/C17H18N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17; /h5-8H, 9H2, 1-4H3; /q-1; +1/t24-; /m0./s1
SMILES Code: O=[S](C1=NC2=CC(OC)=CC=C2[N-]1)CC3=NC=C(C)C(OC)=C3C.[Na+]
H-199; H 199; H199; 18sodium; 18-sodium; 18 sodium; Nexium IV
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