Comparison

Mometasone furoate

Item no. V1701-500mg
Manufacturer InvivoChem LLC
CASRN 83919-23-7
Amount 500 mg
Quantity options 100 mg 1 g 250 mg 25 mg 50 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V1701CAS #:83919-23-7Purity >=98%

Description: Mometasone Furoate (formerly also known as SCH-32088) is a potent glucocorticoid receptor agonist used topically to reduce inflammation of the skin or in the airways. Like other topical corticosteroids, mometasone furoate has anti-inflammatory, antipruritic, and vasoconstrictive properties. The mechanism of the anti- inflammatory activity of the topical steroids remains unclear. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle and the integrity of the epidermal barrier.

References: Immunopharmacol Immunotoxicol. 2006; 28(3):491-500; Eur J Pharmacol. 2005 Nov 7; 524(1-3):155-8.


Molecular Weight (MW)
521.43
Formula
C27H30Cl2O6
CAS No.
83919-23-7
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 6 mg/mL (11.5 mM)
Water:< 1 mg/mL
Ethanol:< 1 mg/mL
Other info
Chemical Name: (8S, 9R, 10S, 11S, 13S, 14S, 16R, 17R)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10, 13, 16-trimethyl-3-oxo-6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl furan-2-carboxylate
InChi Key: WOFMFGQZHJDGCX-ZULDAHANSA-N
InChi Code: InChI=1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16, 2)26(18, 29)21(31)13-25(19, 3)27(15, 22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5, 8-10, 12, 15, 18-19, 21, 31H, 6-7, 11, 13-14H2, 1-3H3/t15-, 18+, 19+, 21+, 24+, 25+, 26+, 27+/m1/s1
SMILES Code: O=C(C1=CC=CO1)O[C]2(C(CCl)=O)[CH](C)C[C]3([H])[C]4([H])CCC5=CC(C=C[C]5(C)[C]4(Cl)[CH](O)C[C]23C)=O
Synonyms
SCH-32088; Sch-32088; Sch32088; Sch 32088; ELOCON brand of mometasone furoate cream (0.1)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
available

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