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Description: Betamethasone Valerate (also known as BV or BET, betamethasone 17-valerate) is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive activities. Betamethasone valerate is a commonly used anti-inflammatory corticosteroid, used to manufacture dermatological drug products for topical applications. Its IC50 in normal rats is 3.4+/-0.5 nM. Betamethasone Valerate can reduce glucose-6-phosphate dehydrogenase (G-6-PDH) activity in vitro.
References: Spectrochim Acta A Mol Biomol Spectrosc. 2015 Apr 5; 140:294-304; Br Med J. 1971 Jul 10; 3(5766):84-6; J Pharm Biomed Anal. 2011 Jan 5; 54(1):242-7.
Chemical Name: (8S, 9R, 10S, 11S, 13S, 14S, 16S, 17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10, 13, 16-trimethyl-3-oxo-6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate
InChi Key: SNHRLVCMMWUAJD-SUYDQAKGSA-N
InChi Code: InChI=1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17, 3)26(19, 28)21(31)14-25(20, 27)4/h10-11, 13, 16, 19-21, 29, 31H, 5-9, 12, 14-15H2, 1-4H3/t16-, 19-, 20-, 21-, 24-, 25-, 26-, 27-/m0/s1
SMILES Code: O=C1C=C[C]2([C]3([CH](C[C]4([C](OC(CCCC)=O)([CH](C[C]4([C]3(CCC2=C1)[H])[H])C)C(CO)=O)C)O)F)C
BV; BET; betamethasone 17-valerate; Betamethasone Valerate; Betoid; Valison; 9alpha-Fluo; Valisone; Bedermin; Betneval; Beta-Val; Bextasol; Dermosol; Stanoval
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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