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Description: Flumethasone (also known as Flumetasone; RS-2177; NSC-54702), a topically used corticosteroid, is a potent glucocorticoid receptor agonist. It reduces insulin-dependent glucose utilization in calves at 24 hours after treatment. Flumethasone combined with sodium ceftiofur reduces the mortality rate in calves with severe acute bronchopneumonia and their clinical and haematological parameters returns to normal significantly faster than in the control calves.
References: Zentralbl Veterinarmed A. 1998 Sep; 45(6-7):441-3; J Am Vet Med Assoc. 1996 May 15; 208(10):1702-4.
Related CAS: 2823-42-9 (Flumethasone 21-acetate); 2002-29-1 (pivalate)
Chemical Name: (6S, 8S, 9R, 10S, 11S, 13S, 14S, 16R, 17R)-6, 9-difluoro-11, 17-dihydroxy-17-(2-hydroxyacetyl)-10, 13, 16-trimethyl-6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
InChi Key: WXURHACBFYSXBI-GQKYHHCASA-N
InChi Code: InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15, 2)21(14, 24)17(27)9-20(13, 3)22(11, 29)18(28)10-25/h4-5, 7, 11, 13-14, 16-17, 25, 27, 29H, 6, 8-10H2, 1-3H3/t11-, 13+, 14+, 16+, 17+, 19+, 20+, 21+, 22+/m1/s1
SMILES Code: O=C1C=C[C]2(C)[C]3(F)[CH](O)C[C]4(C)[C](C(CO)=O)(O)[CH](C)C[C]4([H])[C]3([H])C[CH](F)C2=C1
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
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