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Clomifene citrate (Clomiphene)

Clomifene citrate (Clomiphene)

Item no.	V1740-2g
Manufacturer	InvivoChem LLC
CASRN	50-41-9
Amount	2 g
Quantity options	100 g 10 g 1 g 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1740CAS #:50-41-9Purity >=98% Description: Clomifene Citrate (also known as NSC 35770; Clomiphene) is a potent SERM (selective estrogen receptor modulator) used in the treatment of ovulation induction. It acts by inhibiting the action of estrogen on the pituitary. Clomiphene Citrate is an activator of PKC. Clomifene competes with 3H-QNB and 3H-nitrendipine for their binding to the receptor in the membrane fractions from the urinary bladder and myometrium. Clomifene inhibits estrogen receptors in the hypothalamus, inhibiting negative feedback of estrogen on gonadotropinrelease. References: Cancer Chemother Pharmacol. 1990; 26(4):310-2; Dongwuxue Yanjiu. 2013 Oct; 34(5):487-92. Related CAS #: 911-45-5 (free base) 50-41-9 (citrate)
Molecular Weight (MW)	598.08
Formula	C26H28ClNO.C6H8O7
CAS No.	50-41-9
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 120 mg/mL (200.6 mM)
	Water: < 1 mg/mL
	Ethanol: 11 mg/mL (18.4 mM)
Solubility (In vivo)	Chemical Name: 2-[4-(2-chloro-1, 2-diphenylethenyl)phenoxy]-N, N-diethylethanamine InChi Key: GKIRPKYJQBWNGO-QPLCGJKRSA-N InChi Code: InChI=1S/C26H28ClNO/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23/h5-18H, 3-4, 19-20H2, 1-2H3/b26-25- SMILES Code: CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3
Synonyms	NSC-35770; NSC35770; NSC 35770; Clomiphene; D; Chloramiphene; Omifin; Citrate; Clomiphene; Clomid; Androxal; Clomide; Clomifen; Clostilbegit; Dyneric; Gravosan; Klostilbegit; Serophene

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