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benazepril-hcl

benazepril-hcl

Item no.	V1787-250mg
Manufacturer	InvivoChem LLC
CASRN	86541-74-4
Amount	250 mg
Quantity options	100 mg 10 g 1 g 2 g 500 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1787CAS #:86541-74-4Purity >=98% Description: Benazepril HCl (formerly also known as CGS 14824A HCl; brand name: Lotensin among others), a prodrug that can be metabolized to its active form benazeprilat, is a novel and potent angiotensin I converting enzyme (ACE) inhibitor that has been widely used primarily in treatment of hypertension. The mechanism of action of thie drug is to prevent the catalytic conversion of angiotensin I to angiotensin II and in turn causes vasodilation and an increase in capillary blood volume. Benazepril hydrochloride dose-dependently inhibits the increase in the blood pressure caused by continuous norepinephrine infusion in spontaneously hypertensive rats and suppresses in seizures. References: Arzneimittelforschung. 1991 Jun; 41(6):602-7; J Vet Med Sci. 2007 Oct; 69(10):1015-23. Related CAS#: 86541-75-5 (free base); 86541-78-8 (Benazeprilat)
Molecular Weight (MW)	460.95
Formula	C24H28N2O5.HCl
CAS No.	86541-74-4 (HCl);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 92 mg/mL (199.6 mM)
	Water: 19 mg/mL (41.2 mM)
	Ethanol: 92 mg/mL (199.6 mM)
Other info	Chemical Name: (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2, 3, 4, 5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride InChi Key: VPSRQEHTHIMDQM-FKLPMGAJSA-N InChi Code: InChI=1S/C24H28N2O5.ClH/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28; /h3-11, 19-20, 25H, 2, 12-16H2, 1H3, (H, 27, 28); 1H/t19-, 20-; /m0./s1 SMILES Code: O=C(O)CN1C([CH](N[CH](C(OCC)=O)CCC2=CC=CC=C2)CCC3=CC=CC=C31)=O.[H]Cl
Synonyms	CGS 14824A HCl; CGS-14824A; CGS14824A; Briem; CGS-14824-A; CGS-14824 A; Cibacene; Cibacen; Labopal; Lotensin

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 250 mg

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Delivery expected until 9/4/2025

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