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enalapril-maleate

enalapril-maleate

Item no.	V1788-500mg
Manufacturer	InvivoChem LLC
CASRN	76095-16-4
Amount	500 mg
Quantity options	10 g 1 g 250 mg 2 g 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1788CAS #:76095-16-4 Purity >=98% Description: Enalapril Maleate (also known as MK-421 Maleate) is a potent nonsulfhydryl angiotensin-converting enzyme (ACE) inhibitor widely used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure. Enalapril Maleate has been used to study diabetic angiopathy in diabetic rats and inhibition of ACE in hog plasma (I50=1.2nM). Enalapril treatment abolishes the deleterious effects of eNOS deficiency on blood pressure (BP), atherosclerosis, and kidney dysfunction in mice. References: Clin Pharm. 1985; 4(1):27-40; J Clin Invest. 2000; 105(4):451-8; Pharmacol Res. 2011; 64(5):482-92. Related CAS#: 84680-54-6 (Enalaprilat Dihydrate); 75847-73-3 (Enalapril free base); 149404-21-7 (Enalapril sodium); 349554-02-5 (Enalapril D5 maleate); 690655-41-5 (NCX899, a NO-releasing derivative of enalapril)
Molecular Weight (MW)	492.52
Formula	C20H28N2O5.C4H4O4
CAS No.	76095-16-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 99 mg/mL (201.0 mM)
	Water: < 1 mg/mL
	Ethanol: 4 mg/mL (8.1 mM)
Other info	Chemical Name: (Z)-but-2-enedioic acid; (2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid InChi Key: OYFJQPXVCSSHAI-QFPUQLAESA-N InChi Code: InChI=1S/C20H28N2O5.C4H4O4/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25; 5-3(6)1-2-4(7)8/h4-6, 8-9, 14, 16-17, 21H, 3, 7, 10-13H2, 1-2H3, (H, 24, 25); 1-2H, (H, 5, 6)(H, 7, 8)/b; 2-1-/t14-, 16-, 17-; /m0./s1 SMILES Code: CCOC(=O)[CH](CCC1=CC=CC=C1)N[CH](C)C(=O)N2CCC[CH]2C(=O)O.C(=C\C(=O)O)\C(=O)O
Synonyms	MK-421 Maleate; Glioten; Vasotec; Baripril; Maleate, Enalapril; MK 421; MK-421; MK421; Renitec; Renitek;

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Amount: 500 mg

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Delivery expected until 9/4/2025

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