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Description: Cilazapril Monohydrate (Ro 31-2848) is a potent angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure. Cilazapril is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is known that the diacid form of Cilazapril is more potent that enalapril at inhibiting ACE.
References: J Pharmacol Sci. 2004 Jan; 94(1):67-72; Life Sci. 1999; 64(3):PL27-39.
Related CAS #: 92077-78-6 (hydrate); 88768-40-5 (free)
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