GW9508

Item no.	V1805-100mg
Manufacturer	InvivoChem LLC
CASRN	885101-89-3
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1805CAS #:885101-89-3Purity >=98% Description: GW9508 is a novel, potent and selective agonist for FFA1 (fatty acid receptor GPR40) with pEC50 of 7.32, and is 100-fold selective against GPR120, it stimulates insulin secretion in a glucose-sensitive manner. GW9508 is a GPR40/120 agonist and is different from the reported GPR40/120 agonist GW1100. When tested with HEK-293 (human embryonic kidney) cells expressing GPR40 or GRP120, GW9508 treatment increased intracellular Ca2+ concentration via activating GPR40/120 in a dose-dependent manner. References: Br J Pharmacol. 2006 Jul; 148(5):619-28; J Endocrinol. 2008 Sep; 198(3):533-40.
Molecular Weight (MW)	347.41
Formula	C22H21NO3
CAS No.	885101-89-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 69 mg/mL (198.6 mM)
	Water: < 1 mg/mL
	Ethanol: 69 mg/mL (198.6 mM)
Synonyms	GW9508; GW-9508; GW 9508.
Other info	Chemical Name: 3-(4-((3-phenoxybenzyl)amino)phenyl)propanoic acid InChi Key: DGENZVKCTGIDRZ-UHFFFAOYSA-N InChi Code: InChI=1S/C22H21NO3/c24-22(25)14-11-17-9-12-19(13-10-17)23-16-18-5-4-8-21(15-18)26-20-6-2-1-3-7-20/h1-10, 12-13, 15, 23H, 11, 14, 16H2, (H, 24, 25) SMILES Code: O=C(O)CCC1=CC=C(NCC2=CC=CC(OC3=CC=CC=C3)=C2)C=C1

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Amount: 100 mg

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