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Description: Finasteride (also known as MK-906) is a potent, reversible, and orally bioactive inhibitor of the rat type II 5 alpha-reductase with Ki of 10.2 nM, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB). It is a medication used for the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB). Finasteride is a type II and type III 5alpha-reductase inhibitor that inhibits type II 5alpha reductase (IC50 = 65 nM). Suppresses the conversion of testosterone to dihydrotestosterone. It reduces prostatic dihydrotestosterone levels and prostate size in vivo.
References: J Steroid Biochem Mol Biol. 1997 Apr; 61(1-2):55-64; Teratology. 1990 Jul; 42(1):91-100.
Related CAS#: 222989-99-3 (Finasteride acetate); 98319-26-7 (free)
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