« Back
Home /
Maraviroc (UK427857)

Maraviroc (UK427857)

Item no.	V1810-100mg
Manufacturer	InvivoChem LLC
CASRN	376348-65-1
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1810CAS #:376348-65-1Purity >=98% Description: Maraviroc (also known as UK-427857) is a potent, selective and non-competitive CCR5 antagonist for MIP-1alpha, MIP-1beta and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM in cell-free assays, respectively. Maraviroc is used as an antiviral agent for the treatment of HIV. In HeLa P4 cells, maraviroc inhibited binding of viral envelope gp120 to CCR5 with IC50 value of 11 nM and prevented the membrane fusion events, which were necessary for viral entry. References: Antimicrob Agents Chemother. 2005 Nov; 49(11):4721-32; PLoS One. 2011; 6(6):e20209.
Molecular Weight (MW)	513.67
Formula	C29H41F2N5O
CAS No.	376348-65-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (194.7 mM)
	Water:< 1 mg/mL
	Ethanol: 100 mg/mL (194.7 mM)
Solubility (In vivo)	2% DMSO+Corn oil: 10 mg/mL
Synonyms	UK427857; UK-427, 857; UK-427857; UK-427, 857; UK 427857; Selzentry; Celsentri; Selzentry;

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 mg

available

Delivery expected until 9/4/2025

Express Delivery: Save 15 days

Compare

Add to wishlist

Get an offer