Comparison

Adefovir Dipivoxil (GS 0840)

Item no. V1815-10g
Manufacturer InvivoChem LLC
CASRN 142340-99-6
Amount 10 g
Quantity options 100 mg 1 g 250 mg 25 mg 500 mg 50 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V1815CAS #:142340-99-6 Purity >=98%

Description: Adefovir Dipivoxil (also known as GS 0840 and GS-0840; trade names Preveon and Hepsera), the dipivoxil formulation of adefovir, is a reverse transcriptase inhibitor, used in the treatment of chronic hepatitis B virus (HBV). It is an antiviral acyclic nucleoside phosphonate (ANP) analog and a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficiency virus (HIV). Adefovir Dipivoxil is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) that works by blocking reverse transcriptase for the treatment of hepatitis B. Adefovir dipivoxil is not effective against HIV-1.

References: Antiviral Res. 2002 Jul; 55(1):27-40.

Related CAS#: 42340-99-6 (Adefovir free acid); 193681-12-8 (Alamifovir); 145514-04-1 (Amdoxovir); 124915-24-8 (Carbovir); 144606-93-9(Carbovir triphosphate); 129556-87-2 (Adefovir monophosphate)

Molecular Weight (MW)
501.47
Formula
C20H32N5O8P
CAS No.
142340-99-6
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 100 mg/mL (199.4 mM)
Water:< 1 mg/mL
Ethanol: 100 mg/mL (199.4 mM)
Other info
Chemical Name: [2-(6-aminopurin-9-yl)ethoxymethyl-(2, 2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2, 2-dimethylpropanoate
InChi Key: WOZSCQDILHKSGG-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H32N5O8P/c1-19(2, 3)17(26)30-11-32-34(28, 33-12-31-18(27)20(4, 5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H, 7-8, 11-13H2, 1-6H3, (H2, 21, 22, 23)
SMILES Code: CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C
Synonyms
GS 0840; GS0840; GS-0840; Hepsera; Preveon. Adefobir; GS-0393; GS-393; GS0393; GS393; GS 0393; GS 393; PMEA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 g
Available: In stock
available

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