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Calcitriol (1,25-Dihydroxyvitamin D3)

Calcitriol (1,25-Dihydroxyvitamin D3)

Item no.	V1857-25mg
Manufacturer	InvivoChem LLC
CASRN	32222-06-3
Amount	25 mg
Quantity options	100 mg 10 mg 1 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1857CAS #:32222-06-3Purity >=98% Description: Calcitriol (RO215535, Topitriol; 1, 25(OH)2D3) is the metabolically/hormonally active form of vitamin D and a vitamin D receptor (VDR) agonist. Calcitriol is converted to metabolites more potent and rapidly acting than other forms of Vitamin D. Calcitriol has played an important role in mineral and skeletal homeostasis by regulating the differentiation, growth and the function of the cell immune system. In vitro studies, Calcitriol has been reported to dose-dependently inhibit the production of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) in human peripheral blood cells (PBMC) stimulated by LPS. References: J Clin Invest. 1984 Oct; 74(4):1451-5; J Biol Chem. 1997 May 2; 272(18):11902-7.
Molecular Weight (MW)	416.64
Formula	C27H44O3
CAS No.	32222-06-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 83 mg/mL (199.2 mM)
	Water: < 1 mg/mL
	Ethanol: 83 mg/mL (199.2 mM)
Other info	Chemical Name: 1alpha, 25-Dihydroxyvitamin D3 InChi Key: GMRQFYUYWCNGIN-GSMZWGLTSA-N InChi Code: InChI=1S/C27H44O3/c1-18(8-6-14-26(3, 4)30)23-12-13-24-20(9-7-15-27(23, 24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11, 18, 22-25, 28-30H, 2, 6-9, 12-17H2, 1, 3-5H3/b20-10+, 21-11-/t18-, 22-, 23-, 24?, 25-, 27-/m1/s1 SMILES Code: O[CH](C/C1=C/C=C2C3CC[CH]([C]3(CCC/2)C)[CH](C)CCCC(C)(O)C)C[CH](O)C1=C
Synonyms	1, 25(OH)2D3; 1, 25(OH)2-D3; 1, 25(OH)2-VD3; 1, 25-Dihydroxyvitamin D3; RO215535, Topitriol; Rocaltrol; Calcijex; Topitriol; Silkis; Soltriol; 1alpha, 25-Dihydroxyvitamin D3; 1alpha, 25(OH)2D3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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Delivery expected until 9/4/2025

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