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Oltipraz (RP 35972; NSC 347901)

Oltipraz (RP 35972; NSC 347901)

Item no.	V1892-100mg
Manufacturer	InvivoChem LLC
CASRN	64224-21-1
Amount	100 mg
Quantity options	1 g 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1892CAS #:64224-21-1 Purity >=98% Description: Oltipraz (RP 35972; NSC 347901), a potential anticancer agent, is a potent Nrf2 activator and an inducer of Phase II detoxification enzymes such as glutathione-S-transferase (GST). Oltipraz is a synthetic, substituted 1, 2-dithiole-3-thione originally used in humans as an antischistosomal agent. Oltipraz has been classified as a monofunctional inducer since it advantageously elevates Phase II detoxification enzymes, while only slightly altering the expression of the Phase I “activating” enzymes. References: Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6):3410-5; Mol Cancer Ther. 2009 Oct; 8(10):2791-802.
Molecular Weight (MW)	226.34
Formula	C8H6N2S3
CAS No.	64224-21-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 39 mg/mL (172.3 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 4-methyl-5-(pyrazin-2-yl)-3H-1, 2-dithiole-3-thione InChi Key: CKNAQFVBEHDJQV-UHFFFAOYSA-N InChi Code: InChI=1S/C8H6N2S3/c1-5-7(12-13-8(5)11)6-4-9-2-3-10-6/h2-4H, 1H3 SMILES Code: S=C1SSC(C2=NC=CN=C2)=C1C
Synonyms	CD-1400; CD1400; CD 1400

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Amount: 100 mg

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