« Back
Home /
Puromycin 2HCl (CL13900)

Puromycin 2HCl (CL13900)

Item no.	V1926-25mg
Manufacturer	InvivoChem LLC
CASRN	58-58-2
Amount	25 mg
Quantity options	100 mg 10 mg 1 g 250 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1926CAS #:58-58-2 Purity >=98% Description: Puromycin 2HCl (CL13900), an analog of aminoacyl-tRNA (anaminonucleoside), is a potent antibiotic which acts as a protein synthesis inhibitor. It inhibits the incorporation of aminoacyl-tRNA into the C-terminal on a synthesizing polypeptide, resulting in the premature termination of the polypeptide chain. Puromycin is toxic to the growth of various eukaryote cells including mammalian cells. Concentrations of puromycin sufficient to inhibit the cell growth of mammalian cells range from 0.5-10 ug/ml. IC90s for puromycin to inhibit the growth of Plasmodium falciparum and Giardia lamblia are 60 ng/ml and 54 ug/ml, respectively. References: Pharmacol Rev. 1964 Sep; 16:223-43; Biol Reprod. 2005 Feb; 72(2):309-15. Related CAS#: 53-79-2 (Puromycin free base); 58-60-6 (Puromycin Aminonucleoside)
Molecular Weight (MW)	544.43
Formula	C22H29N7O5.2HCl
CAS No.	58-58-2 (Puromycin 2HCl);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (183.7 mM)
	Water: 100 mg/mL (183.7 mM)
	Ethanol: < 1 mg/mL
Other info	Chemical Name: (2S)-2-Amino-N-[(2S, 3S, 4R, 5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide dihydrochloride InChi Key: MKSVFGKWZLUTTO-FZFAUISWSA-N InChi Code: InChI=1S/C22H29N7O5.2ClH/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12; ; /h4-7, 10-11, 14-16, 18, 22, 30-31H, 8-9, 23H2, 1-3H3, (H, 27, 32); 2*1H/t14-, 15+, 16+, 18+, 22+; ; /m0../s1 SMILES Code: O=C(N[CH]1[CH](CO)O[CH](N2C=NC3=C(N(C)C)N=CN=C23)[CH]1O)[CH](N)CC4=CC=C(OC)C=C4.[H]Cl.[H]Cl
Synonyms	Puromycin Dihydrochloride; Puromycin 2HCl; CL13900 2HCl; CL-13900 dihydrochloride; CL 13900 dihydrochloride; Puromycine; NSC-3055; NSC3055; NSC 3055

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 25 mg

available

Delivery expected until 10/2/2025

Express Delivery: Save 13 days

Compare

Add to wishlist

Get an offer