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Artesunate

Artesunate

Item no.	V2003-5g
Manufacturer	InvivoChem LLC
CASRN	88495-63-0
Amount	5 g
Quantity options	10 g 1 g 250 mg 2 g 500 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2003CAS #:88495-63-0 Purity >=98% Description: Artesunate, an antimalaria agent, is a semisynthetic derivative of artemisinin with an IC50 of < 5 uM for small cell lung carcinoma cell line H69. It is an active ingredient in the Chinese herb Artemisia annua and has been used in Malaria studies. Artesunate has been tested against 55 cell lines and demonstrated anti-cancer activity. Research shows that conditional expression of CDC25A heightens the sensitivity of tumor cells to artesunate. References: Expert Opin Investig Drugs. 9: 1815-1827, 2000; Mol. Pharmacol. 64: 382-394, 2003.
Molecular Weight (MW)	384.42
Formula	C19H28O8
CAS No.	88495-63-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 10 mM
	Water: N/A
	Ethanol: N/A
Other info	Chemical Name: 4-oxo-4-(((3R, 5aS, 6R, 8aS, 9R, 10S, 12R, 12aR)-3, 6, 9-trimethyldecahydro-12H-3, 12-epoxy[1, 2]dioxepino[4, 3-i]isochromen-10-yl)oxy)butanoic acid InChi Key: FIHJKUPKCHIPAT-AHIGJZGOSA-N InChi Code: InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3, 25-17)26-27-19/h10-13, 16-17H, 4-9H2, 1-3H3, (H, 20, 21)/t10-, 11-, 12+, 13+, 16-, 17-, 18-, 19-/m1/s1 SMILES Code: C[CH]1CC[CH]2[CH](C)[CH](OC(CCC(O)=O)=O)O[CH]3[C]24[CH]1CC[C](OO4)(C)O3
Synonyms	SM-804; WR-256283; HSDB-7458; Armax 200; SM804; WR256283; HSDB7458; SM 804; WR 256283; HSDB 7458

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