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DLin-KC2-DMA

DLin-KC2-DMA

Item no.	V20103-50mg
Manufacturer	InvivoChem LLC
CASRN	1190197-97-7
Amount	50 mg
Quantity options	100 mg 10 mg 1 mg 25 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V20103CAS #:1190197-97-7Purity >=98% Description: DLin-KC2-DMA is novel ionizable and cationic lipid useful for siRNA delivery. DLin-KC2-DMA was formulated and characterized in SNALP and demonstrated to have in vivo activity at siRNA doses as low as 0.01 mg/kg in rodents and 0.1 mg/kg in nonhuman primates. References: Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov; 10(6):781-811.; Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA.Nanomedicine. 2017 May; 13(4):1377-1387. doi: 10.1016/j.nano.2016.12.014. Epub2016 Dec 28. PubMed PMID: 28038954. Related CAS #: 1224373-32-3 (S-isomer) 1224373-36-7 (R-isomer) 1190197-97-7

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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