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SBC-110736

SBC-110736

Item no.	V2106-100mg
Manufacturer	InvivoChem LLC
CASRN	1629166-02-4
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2106CAS #:1629166-02-4 Purity >=98% Description: SBC-110736 is a novel and potent inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9), which has been reported to be able to lower cholesterol levels in mice. PCSK9 plays a major regulatory role in cholesterol homeostasis, mainly by reducing LDLR levels on the plasma membrane. Several studies have determined the potential use of PCSK9 inhibitors in the treatment of hyperlipoproteinemia (commonly called hypercholesterolemia).1348 Furthermore, loss-of-function mutations in the PCSK9 gene result in lower levels of LDL and protection against cardiovascular disease. References: Curr Atheroscler Rep. 2019 Mar 16; 21(5):16.
	Name: SBC-110736 CAS#: 1629166-02-4 Chemical Formula: C26H27N3O2 Exact Mass: 413.2103 Molecular Weight: 413.52 Elemental Analysis: C, 75.52; H, 6.58; N, 10.16; O, 7.74
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: SBC-110736; SBC 110736; SBC110736 Chemical Name: N-[4-(2-Phenyl-4-p-tolyl-piperazine-1-carbonyl)-phenyl]-acetamide InChi Key: PILMFSWQYWYOJC-UHFFFAOYSA-N InChi Code: InChI=1S/C26H27N3O2/c1-19-8-14-24(15-9-19)28-16-17-29(25(18-28)21-6-4-3-5-7-21)26(31)22-10-12-23(13-11-22)27-20(2)30/h3-15, 25H, 16-18H2, 1-2H3, (H, 27, 30) SMILES Code: CC(NC1=CC=C(C(N2C(C3=CC=CC=C3)CN(C4=CC=C(C)C=C4)CC2)=O)C=C1)=O

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Amount: 100 mg

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Delivery expected until 9/4/2025

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