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Description: Gastrodin (Gastrodine), a brain-penetrant anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume, benefits neurodegenerative diseases. Gastrodin is the most important and effective ingredient extracted from Chinese natural herbal Gastrodia elata. Gastrodin (30, 40, and 60 mM) significantly attenuates levels of neurotoxic proinflammatory mediators and proinflammatory cytokines by inhibition of the NF-kappaB signaling pathway and phosphorylation of MAPKs in LPS-stimulated microglial cells.
References: PLoS One. 2011; 6(7):e21891; Biochem Pharmacol. 2013 Apr 15; 85(8):1124-33; J Ethnopharmacol. 1997 Mar; 56(1):45-54.
Chemical Name: 4-(hydroxymethyl)phenyl beta-D-glucopyranoside
InChi Key: PUQSUZTXKPLAPR-UJPOAAIJSA-N
InChi Code: InChI=1S/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4, 9-18H, 5-6H2/t9-, 10-, 11+, 12-, 13-/m1/s1
SMILES Code: O[CH]([CH]([CH]([CH](CO)O1)O)O)[CH]1OC2=CC=C(CO)C=C2
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
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