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arbidol-hcl

arbidol-hcl

Item no.	V2388-50mg
Manufacturer	InvivoChem LLC
CASRN	131707-23-8
Amount	50 mg
Quantity options	100 mg 10 g 10 mg 1 g 250 mg 25 g 25 mg 2 g 500 mg 5 g 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2388CAS #:131707-23-8 Purity >=98% Description: Umifenovir (Arbidol) HCl is a broad-spectrum antiviral compound that blocks viral fusion, used in Russia and China for the treatment of influenza and other respiratory viral infections. Arbidol inhibits the cell entry of HCV pseudoparticles of genotypes 1a, 1b, and 2a in a dose-dependent fashion. Arbidol also displays a dose-dependent inhibition of HCV membrane fusion, as assayed by using HCV pseudoparticles (HCVpp) and fluorescent liposomes. Arbidol is found to present potent inhibitory activity against enveloped and non-enveloped RNA viruses, including FLU-A, RSV, HRV 14 and CVB3 when added before, during, or after viral infection, with IC50 ranging from 2.7 to 13.8 mg/mL. References: Biochemistry. 2007 May 22; 46(20):6050-9; Arch Virol. 2007; 152(8):1447-55; J Med Virol. 2012 Jan; 84(1):170-81. Related CAS #: 131707-23-8 (HCl) 131707-25-0 (free base) 868364-57-2 (HCl hydrate)
Molecular Weight (MW)	513.88
Formula	C22H25BrN2O3S.HCl
CAS No.	131707-23-8
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 103 mg/mL (200.4 mM)
	Water: < 1 mg/mL
	Ethanol: 22 mg/mL (42.8 mM)
Other info	Chemical Name: ethyl 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-indole-3-carboxylate hydrochloride InChi Key: OMZHXQXQJGCSKN-UHFFFAOYSA-N InChi Code: InChI=1S/C22H25BrN2O3S.ClH/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3; /h6-11, 26H, 5, 12-13H2, 1-4H3; 1H SMILES Code: O=C(C1=C(CSC2=CC=CC=C2)N(C)C3=C1C(CN(C)C)=C(O)C(Br)=C3)OCC.[H]Cl
Synonyms	Umifenovir hydrochloride; arbidol

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Amount: 50 mg

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