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Peramivir Trihydrate (RWJ-270201; BCX-1812)

Peramivir Trihydrate (RWJ-270201; BCX-1812)

Item no.	V2442-50mg
Manufacturer	InvivoChem LLC
CASRN	1041434-82-5
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2442CAS #:1041434-82-5 Purity >=98% Description: Peramivir Trihydrate (also known as BCX-1812, RWJ-270201, S-021812) is a trihydrate form of the antiviral agent peramivir which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM. Peramivir protects mice against severe disease outcomes following infection with highly pathogenic avian influenza and multi-dose treatment was efficacious in ferrets. Peramivir combined with Oseltamivir perform better than suboptimal doses of each compound alone to treat influenza infections in mice. Peramivir (30 mg/kg) is effective in promoting the survival of mice infected with systemically replicating H5N1 virus. References: Virology. 2008 Apr 25; 374(1):198-209; Antiviral Res. 2010 Oct; 88(1):38-44; Antiviral Res. 2008 Nov; 80(2):150-7. Related CAS #: 330600-85-6 (free) 1041434-82-5 (hydrate)
Molecular Weight (MW)	382.45
Formula	C15H28N4O4.3H2O
CAS No.	1041434-82-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: < 1 mg/mL
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
SMILES	O[CH]1[C]([CH](C(CC)CC)NC(C)=O)([H])[CH](NC(N)=N)C[CH]1C(O)=O.[H]O.[H]O.[H]O
Synonyms	BCX-1812, RWJ-270201, S-021812; BCX1812; BCX 1812; RWJ 270201; RWJ270201; Peramivir. Brand name: Rapivab; Rapiacta and Peramiflu

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Amount: 50 mg

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