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METFORMIN HCL

METFORMIN HCL

Item no.	V2532-50g
Manufacturer	InvivoChem LLC
CASRN	1115-70-4
Amount	50 g
Quantity options	100 g 15 mg 200 g 25 g 500 g 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2532CAS #:1115-70-4Purity >=98% Description: Metformin HCl is a hypoglycemic medication used in the treatment of type 2 diabetes (non-insulin-dependent diabetes mellitus). It decreases hyperglycemia in hepatocytes primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). Metformin activates AMPK in hepatocytes, as a result, acetyl-CoA carboxylase (ACC) activity is reduced, fatty acid oxidation is induced, and expression of lipogenic enzymes is suppressed. References: J Clin Invest. 2001 Oct; 108(8):1167-74; Science. 2005 Dec 9; 310(5754):1642-6. Related CAS #: 1115-70-4 (HCl) 657-24-9 (free base)
Molecular Weight (MW)	165.62
Formula	C4H11N5.HCl
CAS No.	1115-70-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 33 mg/mL (199.3 mM)
	Water: 33 mg/mL (199.3 mM)
	Ethanol: < 1 mg/mL
Solubility (In vivo)	Chemical Name: 1, 1-Dimethylbiguanide hydrochloride InChi Key: OETHQSJEHLVLGH-UHFFFAOYSA-N InChi Code: InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6; /h1-2H3, (H5, 5, 6, 7, 8); 1H SMILES Code: N=C(NC(N)=N)N(C)C.[H]Cl
Synonyms	1, 1-Dimethylbiguanide hydrochloride; ADX-155; EFB-0027; EX-404; La-6023; SMP-862; ADX 155; EFB 0027; EX 404; La 6023; SMP 862; ADX155; EFB0027; EX404; La6023; SMP862; Fortamet

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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