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Nemiralisib (GSK2269557)

Nemiralisib (GSK2269557)

Item no.	V2539-50mg
Manufacturer	InvivoChem LLC
CASRN	1254036-71-9
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2539CAS #:1254036-71-9 Purity >=98% Description: Nemiralisib (GSK-2269557) is a novel, potent and selective PI3Kdelta inhibitor with pKi of 9.9. It is active in a disease relevant brown Norway rat acute OVA model of Th2-driven lung inflammation. PI3Kdelta is highly enriched in leukocytes, making it an attractive target for the treatment of inflammatory conditions, such as asthma, 6 chronic obstructive pulmonary disease (COPD), and autoimmune diseases. GSK-2269557 is is currently in clinical trials for the treatment of respiratory diseases such as asthma and COPD. Description: Nemiralisib (Description: Nemiralisib (Nemiralisib (GSK-2269557) is a novel, potent and selective PI3Kdelta inhibitor with pKi of 9.9. It is active in a disease relevant brown Norway rat acute OVA model of Th2-driven lung inflammation. PI3Kdelta is highly enriched in leukocytes, making it an attractive target for the treatment of inflammatory conditions, such as asthma, 6 chronic obstructive pulmonary disease (COPD), and autoimmune diseases. GSK-2269557 is is currently in clinical trials for the treatment of respiratory diseases such as asthma and COPD. References: J Med Chem. 2015 Sep 24; 58(18):7381-99. References:References: Related CAS#: 1254036-77-5 (HCl); 1254036-71-9 (free base)

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Amount: 50 mg

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Delivery expected until 9/4/2025

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