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SB-334867

SB-334867

Item no.	V2577-50mg
Manufacturer	InvivoChem LLC
CASRN	792173-99-0
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2577CAS #:792173-99-0Purity >=98% Description: SB-334867 is a novel, non-peptide, selective orexin-1 (OX1) receptor antagonist with a pKb value of 7.2. It was the first non-peptide antagonist developed that is selective for the orexin receptor subtype OX1, with around 50x selectivity for OX1 over OX2 receptors. It has been shown to produce sedative and anorectic effects in animals, and has been useful in characterising the orexinergic regulation of brain systems involved with appetite and sleep, as well as other physiological processes. Description: References: Br J Pharmacol. 2001 Mar; 132(6):1179-82; Neuropsychopharmacology. 2007 Apr; 32(4):786-92. References: Related CAS#: 792173-99-0 (free base); 249889-64-3 (HCl) 792173-99-0 (free base); 249889-64-3 (HCl)
Molecular Weight (MW)	319.32
Formula	C17H13N5O2
CAS No.	792173-99-0 (free base);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 63 mg/mL (197.29 mM)
	Water: < 1 mg/mL
	Ethanol: 3 mg/mL warmed (9.39 mM)
Solubility (In vivo)	1% CMC Na: 30mg/mL
Synonyms	SB334867A; SB334867; SB 334867; SB334867 HCl; SB334867 hydrochloride; SB-334867A; SB 334867A;

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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