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SB408124 HCl

SB408124 HCl

Item no.	V2582-25mg
Manufacturer	InvivoChem LLC
CASRN	1431697-90-3
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2582CAS #:1431697-90-3 Purity >=98% Description: SB408124 HCl is a potent, novel, selective, non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, it exhibits 50-fold selectivity over OX2 receptor. Pre-treated with SB408124 before orexin A in primary astrocyte cultures from the rat cerebral cortex remarkably decreased the orexin A stimulatory activity on forskolin and basal-induced cAMP production. Description: References: Br J Pharmacol. 2004; 141:340-6.; Pharmacol Rep. 2011; 63(3):717-23; Pflugers Arch. 2012; 463(4):531-6. References: Related CAS#: 288150-92-5 (free base); 1431697-90-3 (HCl) 1431697-90-3 (HCl)
Molecular Weight (MW)	392.83
Formula	C19H19ClF2N4O
CAS No.	1431697-90-3 (HCl);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mM
	Water: N/A
	Ethanol: < 1 mg/mL
Other info	Chemical Name: N-(6, 8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea InChi Key: JTARFZSNUAGHRB-UHFFFAOYSA-N InChi Code: InChI=1S/C19H18F2N4O/c1-11-8-17(15-9-12(20)10-16(21)18(15)22-11)24-19(26)23-13-4-6-14(7-5-13)25(2)3/h4-10H, 1-3H3, (H2, 22, 23, 24, 26) SMILES Code: O=C(NC1=CC=C(N(C)C)C=C1)NC2=CC(C)=NC3=C(F)C=C(F)C=C23
Synonyms	SB-408124; SB 408124; SB408124 HCl

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Amount: 25 mg

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Delivery expected until 9/4/2025

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