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l755507

l755507

Item no.	V2591-250mg
Manufacturer	InvivoChem LLC
CASRN	159182-43-1
Amount	250 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2591CAS #:159182-43-1Purity >=98% Description: L-755, 507 is identified as a potent and selective beta3 adrenergic receptor partial agonist with EC50 of 0.43 nM, it displayed > 1000-fold selective over beta1- and beta2-adrenoceptors (EC50 values are 0.43, 580 and > 10000 nM for activation of cloned human beta3-, beta1- and beta2-adrenoceptors respectively). It is also recently identified to enhance CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs) and other cell types. References: Bioorg Med Chem Lett. 1998 May 5; 8(9):1107-12; J Clin Invest. 1998 Jun 1; 101(11):2387-93; Cell Stem Cell. 2015 Feb 5; 16(2):142-7.
Molecular Weight (MW)	584.73
Formula	C30H40N4O6S
CAS No.	159182-43-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (171.0 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 1-hexyl-3-[4-[[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]sulfamoyl]phenyl]urea InChi Key: NYYJKMXNVNFOFQ-MHZLTWQESA-N InChi Code: InChI=1S/C30H40N4O6S/c1-2-3-4-5-19-32-30(37)33-24-10-16-29(17-11-24)41(38, 39)34-25-8-6-23(7-9-25)18-20-31-21-27(36)22-40-28-14-12-26(35)13-15-28/h6-17, 27, 31, 34-36H, 2-5, 18-22H2, 1H3, (H2, 32, 33, 37)/t27-/m0/s1 SMILES Code: O=C(NC1=CC=C(S(=O)(NC2=CC=C(CCNC[CH](O)COC3=CC=C(O)C=C3)C=C2)=O)C=C1)NCCCCCC
Synonyms	L-755507; L 755507; L755507

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Amount: 250 mg

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Delivery expected until 9/4/2025

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