« Back
Home /
RRx-001 (ABDNAZ)

RRx-001 (ABDNAZ)

Item no.	V2621-50mg
Manufacturer	InvivoChem LLC
CASRN	925206-65-1
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2621CAS #:925206-65-1Purity >=98% Description: RRx-001 (ABDNAZ) is a novel hypoxia-selective epigenetic modulator with potential radiosensitizing activity. It inhibits glucose 6-phosphate dehydrogenase(G6PD) in human tumor cells, binds hemoglobin and drives RBC-mediated redox reactions under hypoxia. RRx-001 is a novel, systemically non-toxic, epigenetic anticancer agent for multiple tumour types, with activity mediated through increased nitric oxide (NO) production and PPP inhibition. RRx-001is a novel, nonexplosive molecule modified from a class of solid rocket propellants, has shown promise as a novel cancer therapeutic agent in a number of cell lines and tumor models. References: Malar J. 2015 May 28; 14:218; Drug Metab Dispos. 2012 Sep; 40(9):1810-6.
Molecular Weight (MW)	268.02
Formula	C5H6BrN3O5
CAS No.	925206-65-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 53 mg/mL (197.7 mM)
	Water: < 1 mg/mL
	Ethanol: 23 mg/mL (85.8 mM)
Other info	Chemical Name: 2-bromo-1-(3, 3-dinitroazetidin-1-yl)ethanone InChi Key: JODKFOVZURLVTG-UHFFFAOYSA-N InChi Code: InChI=1S/C5H6BrN3O5/c6-1-4(10)7-2-5(3-7, 8(11)12)9(13)14/h1-3H2 SMILES Code: O=[N+](C1([N+]([O-])=O)CN(C(CBr)=O)C1)[O-]
Synonyms	RRX001; RRX 001; RRx-001; ABDNAZ

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50 mg

available

Delivery expected until 10/2/2025

Express Delivery: Save 2 days

Compare

Add to wishlist

Get an offer