Comparison

Acetyl Tetrapeptide-11

Item no. V2642-25mg
Manufacturer InvivoChem LLC
CASRN 928006-88-6
Amount 25 mg
Quantity options 100 mg 10 mg 1 g 250 mg 500 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V2642CAS #:1051375-19-9 Purity >=98%

Description: Dolutegravir Sodium (formerly also known as GSK-1349572A, Tivicay), the sodium salt of Dolutegravir (also known as GSK1349572, S/GSK1349572) which is a novel, potent and orally bioavailable two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM in a cell-free assay. Dolutegravir is an FDA-approved drug that is used in combination with other medications for the treatment of HIV/AIDS infection. It demonstrated moderate activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. It may also be used, as part of post exposure prophylaxis, to prevent HIV infection following potential exposure.

References: AIDS. 2010 Nov 13; 24(17):2753-5; Antimicrob Agents Chemother. 2011 Feb; 55(2):813-21; ..

Related CAS#: 1051375-16-6 (free); 1051375-19-9 (sodium); Dolutegravir intermediate-1 (1335210-23-5)

1051375-19-9 (sodium); Dolutegravir intermediate-1 (1335210-23-5)
Molecular Weight (MW)
441.36
Formula
C20H19F2N3O5.Na
CAS No.
1051375-19-9 (sodium);
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: > 4.4 mg/mL; < 12.6 mg/mL
Water: < 1 mg/mL
Ethanol:< 1 mg/mL
SMILES
O=C(C1=CN(C2=C(O)C1=O)C[C]3([H])OCC[CH](C)N3C2=O)[N-]CC4=CC=C(F)C=C4F.[Na+]
Synonyms
GSK-1349572A; GSK1349572 sodium; GSK-1349572 sodium; GSK 1349572 sodium; Dolutegravir Sodium

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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