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Vardenafil

Vardenafil

Item no.	V2647-500mg
Manufacturer	InvivoChem LLC
CASRN	224785-90-4
Amount	500 mg
Quantity options	100 mg 1 g 250 mg 25 mg 2 g 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2647CAS #:224785-90-4Purity >=98% Description: Vardenafil (also known as BAY 38-9456; trade names: Levitra; Staxyn; Vivanza) is a novel and potent PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively. Vardenafil is used for treating erectile dysfunction. It is clinically approved for treatment of erectile dysfunction in men, including diabetic and postprostatectomy patients. Vardenafil's indications and contraindications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's. Description: References: Int J Impot Res. 2001 Oct; 13(5):282-90; Neuroscience. 2002; 113(2):351-61. References: Related CAS#: 224789-15-5 (2HCl); 330808-88-3 (HCl trihydrate)
Molecular Weight (MW)	488.6
Formula	C23H32N6O4S
CAS No.	224785-90-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mM
	Water: N/A
	Ethanol: N/A
Solubility (In vivo)	Chemical Name: 2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propyl-3, 5, 6, 7-tetrahydro-4H-5l4-imidazo[1, 5-a][1, 3, 5]triazin-4-one InChi Key: UWRWYSQUBZFWPU-UHFFFAOYSA-N InChi Code: InChI=1S/C23H35N6O4S/c1-5-10-27-16-21-24-22(25-23(30)29(21, 4)17-27)19-15-18(8-9-20(19)33-7-3)34(31, 32)28-13-11-26(6-2)12-14-28/h8-9, 15-16H, 5-7, 10-14, 17H2, 1-4H3, (H, 24, 25, 30) SMILES Code: O=C(NC(C1=CC(S(=O)(N2CCN(CC)CC2)=O)=CC=C1OCC)=N3)[N]4(C)C3=CN(CCC)C4
Synonyms	BAY38-9456; BAY 38-9456; BAY-38-9456; BAY38-9456; trade names: Levitra; Staxyn; Vivanza;

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Amount: 500 mg

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