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Fomepizole

Fomepizole

Item no.	V2677-1g
Manufacturer	InvivoChem LLC
CASRN	7554-65-6
Amount	1 g
Quantity options	10 g 2 g 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2677CAS #:7554-65-6Purity >=98% Description: Fomepizole (also known as 4-methylpyrazole, Antizol, Antizol-Vet) is a competitive inhibitor of alcohol dehydrogenase, an enzyme that catalyzes the initial steps in the metabolism of ethylene glycol, ethanol and methanol to their toxic metabolites. Fomepizole is an ADH (alcohol dehydrogenase) inhibitor. It can be used as an antidote in methanol and ethylene glycol poisoning. Fomepizole is used for the treatment of ethylene glycol and methanol poisonings in adults. Fomepizole is a competitive antagonist of alcohol dehydrogenase with a binding affinity > 8000 times that of ethanol. References: Pediatrics. 2001 Jan; 107(1):170; Ann Emerg Med. 2009 Apr; 53(4):439-450.e10.
Molecular Weight (MW)	82.1
Formula	C4H6N2
CAS No.	7554-65-6
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: N/A
	Water: 146 mg/mL
	Ethanol: N/A
SMILES	CC1=CNN=C1
Synonyms	4-methylpyrazole, Antizol; Fomepizole; Fomepizolum

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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