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Description: Tamsulosin HCl, a marketed drug, is a potent and selective alpha1a adrenergic receptor antagonist used for the treatment of benign prostatic hyperplasia (BPH). It has preferential selectivity for the alpha1A receptor in the prostate versus the alpha1B receptor in the blood vessels. Tamsulosin-treated patients had a 0.30-fold lower risk of developing acute urinary retention compared with control patients. Tamsulosin can be recommended for treating men after catheterization for AUR, and can reduce the likelihood of the need for re-catheterization.
References: Int J Urol. 2014 Feb; 21(2):164-8; BJU Int. 2005 Feb; 95(3):354-7.
Related CAS#:106133-20-4 (free); 94666-07-6 (racemic mixture)
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