TH5487

Item no.	V31359-1g
Manufacturer	InvivoChem LLC
CASRN	2304947-71-3
Amount	1 g
Quantity options	100 mg 10 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V31359CAS #:2304947-71-3Purity >=98% Description: TH5487 is a novel, potent and selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor with an IC50 of 342 nM. TH5487 stops OGG1 from recognizing its DNA substrate, inhibits DNA repair and modifies OGG1 chromatin dynamics, which results in the inhibition of proinflammatory pathway genes. References: Visnes T, et al. Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation. Science. 2018 Nov 16; 362(6416):834-839.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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