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Description: diABZI STING agonist-3 is a potent and selective stimulator of interferon genes (STING) receptor agonist with an EC50s of 130 for human PBMCs. It is able to activate STING and stimulate the secretion of IFNbeta, IL-6, TNF, and KC/GROalpha, exhibiting durable anti-tumour effects.
References: Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature 2018 Dec; 564(7736):439-443.
Related CAS #: 2138299-34-8 (HCl) 2138498-18-5 (free base)
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