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tubulysin-b

tubulysin-b

Item no.	V31866-250mg
Manufacturer	InvivoChem LLC
CASRN	205304-87-6
Amount	250 mg
Quantity options	100 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V31866CAS #:205304-87-6Purity >=98% Description: Tubulysin B, a naturally occuring compound extracted from the myxobacteria Archangium geophyra and Angiococcus disciformis, is a highly cytotoxic peptide which acts as a potent microtubule destabilizing agents. Tubulysin B has IC50 in the picomolar range against many cancer cell lines, including those with multidrug resistant properties.Tubulysin B is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. References: 1. LeamonCP, et al. Prostate-Specific Membrane Antigen-Specific AntitumorActivity of a Self-Immolative Tubulysin Conjugate. Bioconjug Chem. 2019Jun 19; 30(6):1805-1813. 2. VlahovIR, et al. Acid mediated formation of an N-acyliminium ion fromtubulysins: a new methodology for the synthesis of natural tubulysinsand their analogs. Bioorg Med Chem Lett. 2011 Nov 15; 21(22):6778-81.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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Delivery expected until 10/2/2025

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