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azd2098

azd2098

Item no.	V3218-25mg
Manufacturer	InvivoChem LLC
CASRN	566203-88-1
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3218CAS #:566203-88-1Purity >=98% Description: AZD2098 is a potent antagonist of CC-chemokine receptor 4 (CCR4) that has been used for asthma research. It was discovered by throughput screen (HTS) of a subset of the AstraZeneca compound bank. As a hit with a lead-like profile, it was an excellent starting point for a CCR4 receptor antagonist program and enabled the rapid progression through the Lead Identification and Lead Optimization phases resulting in the discovery of two bioavailable CCR4 receptor antagonist candidate drugs with one of them being AZD2098. It targets CCR4 which is found on immune cells and helps direct cell trafficking of various types of leukocytes. Description: References: ACS Med Chem Lett. 2017 Sep 1; 8(9):981-986. References:
Molecular Weight (MW)	334.17
Formula	C11H9Cl2N3O3S
CAS No.	566203-88-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 10mM
	Water: N/A
	Ethanol: N/A
Chemical Name	2, 3-Dichloro-N-(3-methoxypyrazin-2-yl)benzenesulfonamide
Synonyms	AZD2098; AZD 2098; AZD-2098
SMILES Code	O=S(C1=CC=CC(Cl)=C1Cl)(NC2=NC=CN=C2OC)=O

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Amount: 25 mg

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