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ulodesine-bcx4208

ulodesine-bcx4208

Item no.	V3307-100mg
Manufacturer	InvivoChem LLC
CASRN	548486-59-5
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3307CAS #:548486-59-5Purity >=98% Description: Ulodesine (formerly also known as BCX4208) is a novel and potent inhibitor of purine nucleoside phosphorylase (PNP) with an IC50 of 0.5 nM. It is is currently being developed by Biocryst as a once-daily oral, chronic treatment for gout. Ulodesine acts at the upstream of xanthine oxidase in the purine metabolism pathway to reduce the production of serum uric acid (sUA) by inhibiting PNP. BCX-4208 is currently in early clinical investigation in psoriasis and gout. Description: References: Expert Opin Investig Drugs. 2018 May; 27(5):437-444. References:
Molecular Weight (MW)	264.28
Formula	C12H16N4O3
CAS No.	548486-59-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: >= 10mg/mL
	Water: N/A
	Ethanol: N/A
Chemical Name	7-(((3R, 4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl)methyl)-3H-pyrrolo[3, 2-d]pyrimidin-4(5H)-one
Synonyms	BCX4208; BCX 4208; BCX-4208; DADMe-immucillin H
SMILES Code	O=C1C(NC=C2CN3C[CH](O)[CH](CO)C3)=C2N=CN1

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 11/6/2025

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