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Description:Terutroban is a selective TP (thromboxane-prostaglandin receptor) receptor antagonist, i.e. a specific antagonist of the thromboxane A(2) and prostaglandin endoperoxide receptors, shown to improve endothelial function after a single administration in patients with coronary artery disease. Terutroban, by chronically improving endothelium-dependent vasodilatation and inhibiting platelet aggregation, may prove useful for preventing cardiovascular events in high-risk patients.
References: Br J Clin Pharmacol. 2011 Jun; 71(6):844-51; Diabetes Metab Res Rev. 2012 Feb; 28(2):132-8.
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