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Pirmenol (Cl-845)

Pirmenol (Cl-845)

Item no.	V3358-100mg
Manufacturer	InvivoChem LLC
CASRN	68252-19-7
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3358CAS #:68252-19-7Purity >=98% Description: Pirmenol (Cl-845) is a potent antiarrhythmic agent that inhibits muscarinic acetylcholine receptor-operated K+ current in the guinea pig heart. The IC50 of Pirmenol for inhibition of Carbachol-induced IK.ACh is 0.1 uM. Pirmenol is active in various experimental arrhythmic models of diverse etiology and has a favorable therapeutic index compared with other class I agents. Pirmenol is highly efficacious whether the arrhythmias were atrial or ventricular in origin, chemically, mechanically or electrically induced or of the automaticity or reentrant types. Description: References: Cardiovasc Drugs Ther. 2004 Sep; 18(5):405-8. References: Related CAS #: 78774-24-0 (racemic) 68252-19-7 (free base) 61477-94-9 (HCl) 82734-31-4 (xHCl)
	CAS#: 68252-19-7 Chemical Formula: C22H30N2O Exact Mass: 338.2358 Molecular Weight: 338.495 Elemental Analysis: C, 78.06; H, 8.93; N, 8.28; O, 4.73
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Chemical Name: 4-((2R, 6S)-2, 6-dimethylpiperidin-1-yl)-1-phenyl-1-(pyridin-2-yl)butan-1-ol; Synonym: Cl 845; Cl-845; Cl845; Pirmavar. SMILES Code: C[CH]1CCC[CH](N1CCCC(C2=CC=CC=C2)(C3=CC=CC=N3)O)C

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Amount: 100 mg

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