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TG4-155

TG4-155

Item no.	V3370-10mg
Manufacturer	InvivoChem LLC
CASRN	1164462-05-8
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3370CAS #:1164462-05-8Purity >=98% Description: TG4-155 is a novel, potent and brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less effective at EP4 (KB = 11.4 uM) and a panel of other receptors and channels.It blocks the induced expression of inflammatory markers in microglial cells treated with the selective EP2 agonist butaprost alone or with LPS and IFNgamma. TG4-155 significantly reduces neurodegeneration in a mouse model of status epilepticus, induced by pilocarpine. It inhibits proliferation, invasion, and inflammatory cytokine expression in cancer cells treated with butaprost. Description: References: The Journal of Biological Chemisty288(13), 9293-9302 (2013). References:
	Name: TG4-155 CAS#: 1164462-05-8 Chemical Formula: C23H26N2O4 Exact Mass: 394.1893 Molecular Weight: 394.47 Elemental Analysis: C, 70.03; H, 6.64; N, 7.10; O, 16.22
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: TG 4-155; TG4155; TG-4155; TG4-155; TG-4-155; TG 4155 Chemical Name: (E)-N-[2-(2-methylindol-1-yl)ethyl]-3-(3, 4, 5-trimethoxyphenyl)prop-2-enamide InChi Key: YBHUXHFZLMFETJ-MDZDMXLPSA-N InChi Code: InChI=1S/C23H26N2O4/c1-16-13-18-7-5-6-8-19(18)25(16)12-11-24-22(26)10-9-17-14-20(27-2)23(29-4)21(15-17)28-3/h5-10, 13-15H, 11-12H2, 1-4H3, (H, 24, 26)/b10-9+ SMILES Code: O=C(NCCN1C(C)=CC2=C1C=CC=C2)/C=C/C3=CC(OC)=C(OC)C(OC)=C3

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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Delivery expected until 9/4/2025

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